A novel method for approximating equilibrium single-channel Ca2+ domains
نویسندگان
چکیده
منابع مشابه
Divergence of Ca2+ selectivity and equilibrium Ca2+ blockade in a Ca2+ release-activated Ca2+ channel
Prevailing models postulate that high Ca(2+) selectivity of Ca(2+) release-activated Ca(2+) (CRAC) channels arises from tight Ca(2+) binding to a high affinity site within the pore, thereby blocking monovalent ion flux. Here, we examined the contribution of high affinity Ca(2+) binding for Ca(2+) selectivity in recombinant Orai3 channels, which function as highly Ca(2+)-selective channels when ...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2015
ISSN: 1471-2202
DOI: 10.1186/1471-2202-16-s1-p162